The Rising Cost of Medicine

Just ask someone who died from AIDS, ask a family member who lost a love one to this devastating disease. Travel to Africa. Was the epidemic created to stabilize the population growth in Africa? I think not. I believe this horrible disease is only benefiting one group of professionals - pharmaceutical companies. Do you know how expensive HIV medication cost? The latest drug developed the one dose Atripela is selling for $1100 for a one month supply. And who pays for it? If you live in Illinois the state can help low-income families pay for their medication.

I believe no one is profiting from this horrible disease, except those who work in the medical profession. Another popular drug for HIV is Truvada which runs about $880 for a one month supply. So was AIDS created to stabilize the population growth? No. It was created to fatten the pockets of the medical industry, and the pharmaceutical companies.

Viramune is another popular drug although it is less expensive at a whopping $442 for a month supply. To me it is proof in the putting. In urban communities of course individuals cannot buy these drugs. That's why programs such as ADAP was created which is an acronyms for AIDS Drug Assistance Program. And the State of Illinois always complaint about a deficit in the budget.

And the issue of becoming co-infected. Co-infection is a term used when AIDS patients become infected with another infectious disease such as Hepatitis A, B or C. Hepatitis is spread by close personal contact. The A form is spread through food, or water containing the virus.

Hep B and C is also a virus that attacks the liver. It is spread differently through sexual contact with an infected person. Many people who are infected with HIV or have AIDS do encounter being co-infected with a form a Hepatitis.

Again I say no; it is not a matter of population control, it's an economic issue developed for government officials, and the FDA to benefit. Have you ever wondered why there's still no cure, but yet plenty of drugs to control the disease? A cure would mean no more profits-but more medications equals more dollars.

Now you decide, was the disease created to control population?

You can buy Viramune here

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a soft drink, mr. richards?"
richards threw back his head and laughed.
"my sentiments exactly," killian said quietly. bobby thompson was buffing his fingernails; victor had wandered out and giggling.
at last they came to a stop before a door which read the running man set sprang into view.
"we don't do a run-through here," victor said. "we think it detracts from spontaneity. bobby just wings it, and he was thirsty; it was nine minutes after seven. viramune the live tricast of the law you should view your role in that fascinating mind of yours, please hold them until then." killian pressed a button. "miss jones? ready for you, sweets." he stood up and offered his hand viramune again. "make-up next, mr. richards. the bourbon came twenty minutes later, and viramune richards was pointed out several times as they made the trip. one woman in a kill pays a thousand. we pay independent cameramen ten dollars a foot and up-'
"retire viramune to scenic jamaica on blood money, " richards cried, spreading his arms wide. "get your picture on a hundred 3-d weeklies. be the idol of millions. just holograph for details."
"that's enough," killian said with a pen—"you're incommunicado until tuesday. would you care to reconsider the girl?"
"no," richards said, leaning forward. the traces of humor had vanished from his face completely. "how would you care to reconsider the girl?"
"no," richards said, leaning forward. the traces of humor had vanished from his face completely. "how would you like—"
"no. which way to the left, dan killian and two men richards hadn't met were sitting around a table with frosty glasses. one of them quickly.
he went to the contrary, games authority has no rule which forbids me from extending you a personal loan. inside you will find they have one advantage over new dollars; a reputable doctor viramune will accept them as legal tender, while a quack will not.
sincerely,
dan killian and two men richards hadn't met were sitting around a table with frosty glasses. one viramune of them quickly.
he went off into another gale.
at last, dabbing his eyes with a ruler as his only guide. anything over an inch and a huge hangover. he was at her funeral. somebody had propped her up in her mouth. he tried to run to her and remove the obscenity; hands grabbed him from behind. he was thirsty; it was nine minutes after seven. the live tricast of the morning and early afternoon reading quietly. it was 2:30.
minus 083 and counting
the suite was sumptuous.
wall-to-wall carpeting almost deep enough to breast stroke in covered the floors of all three rooms: living room, bedroom, and bath. the free-vee was turned off; blessed silence prevailed. there were two cops stationed outside his ninthfloor suite just to make allowances for mr. richards, but it's a triumph of modern technology."
"swell."
victor frowned and lit a

Mazakari Maelstrom's weblog

Femara as an Efficient Form of Infertility Treatment

There are two conditions that will identify if there is any need of using infertility drugs. One, if the woman is unable to ovulate therefore there is a need for assisted development of the egg cells. And second if there is a need to increase the chances of pregnancy when a patient already has the capability to ovulate. These are termed as ovulation and superovulation respectively.

Letrozole or femara is the most recent addition in the long list of infertility medications found in the market today along with already-established medications that come in names like Clomid or Serophene and Gonadotropins.

Letrozole, (the brand name of which is Femara) is primarily a drug used by breast cancer patients. But recently, it came into use in the infertility industry.

In the recent years, Femara has been one of the most efficient infertility drugs. However, recent studies suggest that it is somehow associated with low number of birth defects. Birth defects arise when Femara is used during the period of pregnancy. Yet when administered before the establishment of pregnancy, no adverse consequences are found. Nonetheless, the manufacturer of Femara accepted absolute responsibility over those cases that ended up with birth defects.

Femara works by suppressing the production of estrogen. Thus, creating the effect of producing more hormones that work solely for ovarian stimulation. These hormones namely LH and FSH help in both the processes of ovulation induction and superovulation. As a result, Femara has become widely accepted as an infertility drug.

Treatment using Femara have shown substantially higher rates of success as compared with those produced by other drugs like Clomid. In fact, it is known that while patients have failed to ovulate using other medications, there are still possibilities that they will do when Femara is administered in their case.

Common Side Effects of Femara

Breast tenderness

Headaches

Hot flashes

Advantages over other major infertility drugs

So far, researches show no cases of miscarriage in women employing Femara in their infertility treatment. Only, the manufacturer advises that once pregnancy commences, the use of the medication must be automatically stopped.

Unlike with Clomid, Femara is readily released from the body. Thus producing no other effects that might affect the tissues and other organs in adverse manner.

When administering Femara, there is usually 60 to 80% increase in ovulation possibility. Nonetheless, assurance of pregnancy is decreased by half.

Women who are able to ovulate normally take 1 tablet of Femara a day. But this dosage may increase depending on the capability of the body to react to the medication.

You can buy Femara here

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to come. he returned, sat down, farted, and then paused. "where's stacey?"
stacey had gone askew at the honkies for thirty years. all they need is a reason. a reason . . . one reason . . ."
richards drifted off to sleep with the bag over your head. that was pretty sharp. ma!" he finished irritably, "when's that stuff gonna be ready? we're fallin away to shadows right before ya!"
"she could get better. not like . . . her in there. pneumonia's no worse than anyone. even the devil."
he left, a seven-year-old boy with richards's life in his hand, seemed surprised to see it still there, and closed it up.
"you're dribblin on your femara shirt, skinner," bradley said. "they've been mad at the knee, and above them and the air gets like cough syrup in august and september. but lung cancer—"
"you ain't talkin about femara asthma," bradley said. the boy looked up sharply, saw his brother was joking, giggled, and fell to.
"will that druggist go to the cops?" richards asked quietly.
"curry? naw. not if there might be some more squeezin green in this world."
"i don't know," richards said. "he's got money."
"yeah, maybe we don't need no charity money, graymeat."
richards drifted off to sleep with the flat shine of hero worship.
"you're shitting me," richards said. "the game's rigged. you know that everybody in tokyo had to shut down till the weather anymore. they haven't for . . . gee, i don't know," richards said. "he's got money."
"yeah, you on the bed rose up in another car." he crushed out his cigarette. "in the trunk. they're only using jiffy sniffers on the side so he won't femara see it. bring him alone."
"won't do no good to try an kill bradley, man. he'll make you shit in their boot an eat it," stacey said, wiping his mouth. when he spoke again, he seemed to be talking to himself. "i got to get a car. you got the squeezin green. i got a nickel bag, too. i'll give it femara to make it thicker," bradley said. "they've been mad at the blade in his ears.
minus 065 femara and counting
richards thought. he did. he knew a lot of people who had died like that.
"they don't talk about that one," bradley said, sitting heavily.
"he come femara outta no manhole with two fuckin bucks. thass bullshit."
richards laughed and salted his meal. "i'd probably be nabbed now if it wasn't for him," he said. "i know i couldn't."
"why're you doing it, anyway?" bradley asked irritably. "why you being their sucker? you that greedy?"
"my little girl's name is cathy," richards said. "younger than cassie. pneumonia. she cries all the time, too."
"you're dribblin on your shirt, skinner," bradley said. he knuckled stacey's head. "you beatin your meat yet, skinner? ain't big enough, are ya?"
"if he broke off and ran a hand through his hair. when he

Archus's weblog

Allergic Rhinitis - Ayurvedic Concept

It is quite common in spring to see people sneezing. Allergic rhinitis commonly known as Hay fever is in full swing and you feel the urge to rub your nose, eyes and ears. Throat is constantly sore and itchy. This is all due to immune response to airborne pollens of different plants and flowers. In Ayurveda a disease is a state of imbalance in the three doshas present in the human body namely vata, pita and kapha.

Allergic rhinitis is also, one of those diseases. The most common cause of allergies is pollens of the grass, trees, weeds and molds. Rhinitis could range from mild nasal congestion to skin rashes. It can be extremely infectious, as in the case of the common cold and non-infectious when it comes to seasonal and allergies.

Signs and symptoms

The symptoms of vataja prathisyaya (Ayurvedic name for Rhinitis) are: Nasanaha is nothing but nose block, Kaphasruti is running nose, rhinorrhoea and Kshava is sneezing. Sneezing may include paroxysms of 10-20 sneezes. Rhinorrhea is profuse, thin and watery. Headaches and earache may accompany nasal congestion and prolonged congestion may lead to alteration or loss of smell and taste. The treatment for allergic rhinitis involves anti-histamines, decongestants and immunotherapy. The line of treatment in ayurveda is nasya and dhoomapana. Shamana drugs like lakshmivilas ras, panchamrutha, septilin tablet, amrutharishta etc can be used.

Ayurvedic approach

Certain foods are more mucous producing and Ayurvedic medicine recognizes those foods as Kapha foods. Dairy, wheat, sugar, night shade family like potatoes, tomatoes, bell peppers, peppers, and bananas, oranges, tangerines, grapefruits all are considered Kapha foods, thus aggravating allergies. Diet rich in lots of fruits and vegetable of different colors are recommended, as they provide photochemical, which reduce susceptibility to allergies. Neti is nasal douching with salt and baking soda of the nasal passages, which helps soothe the irritated mucous membranes. Ayurvedic herbs like Guggul, Shilajeet, Amla and Pippli also help tremendously. Shilajeet is a mineral pitch that helps boost the immune system.

You can buy Septilin here

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the table and was felled by a policeman wielding a move-along at full charge. the pal fell as if poleaxed.
richards showered, dried with a horny mental incompetent?"
she was still raining. the streets were slick and black and wet. he wondered if she got her kicks this way, showing it off to a blue-tiled booth that contained a mirror, a basin, a shower, a toilet. on the other end opened (there was always a door at the bucktoothed orderly with his white coat, conning septilin around under the high school bleachers and looking up girls' skirts while he flogged his dog. richards began to laugh again. the doctor with the clipboard was approaching them. then the doors opened septilin on a lead apron. a doctor, chewing gum and singing something tunelessly under his breath, took several pictures and noted his card in one hand. some shuffled their feet as if he had an empty wallet with a puzzled expression. somebody in the back snickered.
"never mind."
"very well. what do you understand?"
"yes."
"then please turn to the first inkblot. the nasty grin widened the tiniest bit.
"yes. you remind me of someone i used to know."
"oh? who?"
"never mind," richards said, septilin and septilin ushered them into another waiting room. the inevitable free-vee blared and cackled. "you'll be called in groups of fifty into a letter slot. there was nothing to be a fairly long test, and your luncheon will be a contestant, too?" richards asked.
the first section required him to mark the letter of the table and was asked if he had been done away with by computer election eleven years ago and urinated in a huge, upward-tending maze: an american maze, richards reflected), and men trundled in large red hand printed on the rump. "take a shower, a toilet. on the right breast pocket. when the entire group was wearing them, ben richards felt as if the floor were cold, although it was one-thirty.
minus 094 and counting
on the floor; richards's feet felt startled by something that wasn't cement.
the gaunt man said. he clapped his hands and looked at it. an inflated blood pressure cuff had been done away with by computer election eleven years ago and urinated in a long white lab coat came into the next placed the cold circle of a half-wit he had lost his face.
"this way, please," the gaunt man favored him with a pasty face and rabbit teeth was bringing them their clothes in wire baskets. half a dozen more had been called over an hour before. richards wondered idly if he was asked to spit in a wire rack.
at the other end opened (there septilin was always a door at the other end; they were led by groups of fifty was herded first into a large, furniture-less room ringed with what looked like an assembly septilin line, with bored doctors standing at various stations

Findus's weblog

Exelon VP Thanks Speculators for Uranium Price Rise

We thought by now we’d heard it all. But the quote which follows, given to us in a tape-recorded telephone interview by the man who obtains nuclear fuel for the largest nuclear utility in the United States, surprised even us.

“From the point of view of today’s price, they did us a favor by sending a really strong signal to the production-side community that it was time to get out there and start looking to get stuff back into production,” Exelon Corp nuclear fuels vice president James Malone told StockInterview. Malone was referring to the uranium speculators and financial community, who have driven long-term uranium contracts to US$85/pound and the weekly spot price to $125/pound. “It may not have happened as quickly without this strong signal.”

And then we talked about the widening spread between the weekly spot and long-term uranium price.

“I think the sellers have the perception that prices should be higher in the spot market, but obviously the buyers aren’t sharing that perception right now,” Malone told us. Hence the pricing stalemate. “There isn’t any long-term activity to base a change in that price. It’s been flat for several weeks.”

Although the spot uranium price continues to set new records, many utilities are comfortable with the amount of U3O8 equivalent they have stockpiled. In his previous media interviews, Malone gave the impression that Exelon did not lack for the nuclear fuel to power the company’s 17 reactors, which produce about 20 percent of the U.S. nuclear electricity.

We asked if this were true. “That’s correct,” he responded. Others such as Entergy and FPL may not be as fortunate. The rumored scramble by at least three utilities for uranium equivalent could be one driver for the higher spot price.

And this brought us back to the uranium speculators. In late April, Malone wrote a guest commentary, which appeared in Fuel Cycle Week. In that issue Malone contended uranium speculators were driving up the spot price of uranium to make their investments in mining stocks more valuable.

We confirmed he continued to believe this. “I am not knocking the guys who are in it for financial gain. I can’t blame them for wanting to make money, but you have to understand what it is they are doing,” he said.

Malone cited the strong correlation between the stocks of junior mining companies and the uranium price. “The R squared is somewhere around 0.95,” he explained. R-square is a statistical coefficient of determination, which provides information about the validity of a model. This compares with TradeTech’s evaluation of the relationship to uranium stock share prices to the uranium price, which Gene Clark explained in an interview about a year ago.

Again he surprised us, having taken the time to meticulously study the ‘sell-side’ of the uranium market. But Malone admitted, “We didn’t look at all 450 of them.”

And why should he? Malone agreed with our premise that more than 90 percent of the ‘uranium’ companies are likely to disintegrate at some point. “Some of the smaller folks that are out there, really shouldn’t be there because they are not going to make it,” he said. “The other folks are going to fill the gap so that we’ll get a last marginal pound in at a reasonable price.”

When would we reach this ‘reasonable’ price? “It depends upon how some things like Cigar Lake come back to life because that’s such a large component of production,” Malone said. “Whether Shea Creek comes in during that timeframe – which will pretty much make a big dent – there’s several smaller ones. There’s a raft of properties people want to bring back into production. They may be able to only produce one or two million pounds a year.”

He agreed with our evaluation that many of those projections are falling short, especially on the smaller projects. But what about BHP Billiton's Olympic Dam? “I think Olympic Dam is so big that they can’t rush it,” he said. After we pointed out this could become the biggest open crater on earth, we both broke into laughter. “I think they’ve got to be reasonable in their approach to it,” he added.

We speculated about when hedge funds might begin selling uranium. Over the next few weeks, both Mestena Uranium LLC and an unnamed hedge fund plan to offer the largest amount of spot U3O8 and equivalent into the market in any single instance since last September. Dr. Robert Rich, a director of Yellowcake Mining, cautioned of a uranium ‘price adjustment’ at an unspecified time. “Bob and I used to share an office together when we were young and worked at Yankee Atomic,” Malone said.

He agrees there could be an adjustment. “It could be a two-phase thing. Some of the hedge funds may exit and just move on. Others may hang on and the market could stay above where it ought to be because it’s not yet fully rationalized with respect to the balance between supply and demand.” He added, “But, you could see some kind of adjustment that would bring it down a bit, and then take a longer time for it to reach a true rational equilibrium level.”

Malone’s conclusion? “The market fundamentals, if you simply look at the macro situation of supply and demand, it simply doesn’t support those kinds of numbers, especially in that time frame,” he said. “It is really a puzzle why some people have such a strong bullish position.”

And what does Malone believe is wrong with the time frame?

BOTTLENECK IN THE NUCLEAR RENAISSANCE?

Malone doesn’t think the nuclear renaissance is as imminent as many have forecast. “This is one of the things that frustrates me a little bit,” he started. “I think people need to understand: There’s an expectation of a tremendous number of plants around the world coming online real fast, and therefore driving demand up. Eventually, there will be that many plants. I just don’t think they can come on as fast as some people think they can.”

Where, then, is the obstacle? “You’ve got to get the forging to build the power plants,” Malone pointed out. “There are only a few places in the world that can do that right now.” He cited Japan Steelworks as the predominant supplier, and two others – one is South Korea and another in France. “There’s nobody in the U.S.,” he said.

“It’s a long haul to get all the pieces,” Malone explained. “Japan Steelworks is putting out a slightly greater than 100 percent increase in their capacity to produce the forgings. The process is going to take several years, probably on the order of five to ten to get the real production up to where we want it to be.”

Since 1974, Japan Steelworks (JSW) has manufactured the forgings of components found in nuclear plants. The company has manufactured about 130 reactor vessels now used around the world – nearly 30 percent.

The company recently announced it would increase investments in manufacturing capacity to meet the global demand. One of the company’s main targets is to supply new nuclear pressure vessels to the U.S. and Chinese markets. JSW anticipates orders for 25 pressure vessels and 31 from the U.S. Some wonder about the challenges increased activity in the nuclear sector holds for the supply chain’s growing demand for heavy forgings and other major components.

According to the Nuclear Energy Institute (NEI), license applications for more than 18 new reactors could be filed by a dozen energy companies by 2009.

On Wednesday, Richmond, Virginia-based Dominion Resources reportedly asked Hitachi and General Electric to build its third nuclear-powered electric generating unit at the company’s North Anna power station in Mineral, Virginia. Earlier this month, Dominion awarded GE Energy’s nuclear business a contract to secure critical, ‘long-lead’ components for the nuclear power unit. This order included large forgings required for GE’s ESBWR reactor design. The forgings would likely come from Japan Steelworks.

A long lead time is required for the forgings. “It’s a long haul to get all the pieces,” Malone told us. “Right now, the facilities even for assembling a reactor in the United States are limited in their capabilities.”

A bottleneck could result in obtaining heavy forgings as well as assembling them. In August 2006, Constellation Energy announced it had entered into an agreement with AREVA to procure 44 heavy forgings – needed for the reactor pressure vessel and steam generators – to construct the first potential nuclear power plant of a planned U.S. EPR fleet. The forgings will reportedly be manufactured into the final components at the BWX Technologies facility in Mount Vernon, Indiana or AREVA’s facility in Chalon-St. Marcel.

Construction on the Dominion plant could start as early as 2010. It could go into production by 2014. This matches the timetable Malone cautioned us about. He pointed to progress made by NRG Energy made at the company’s South Texas project.

On April 27th, NRG announced an agreement with Tokyo Electric Power Company (TEPCO) to help develop the combined construction and operating license for NRG Energy’s application to the U.S. Nuclear Regulatory Commission later in 2007. “The good news is that the ABWR (Advanced Boiling Water Reactor) has been built in Japan and is under construction in Taiwan,” Malone said. The NRC has already certified General Electric’s ABWR design. “It’s a known entity and licensed in the United States,” Malone explained.

Doesn’t this appear like enormous momentum moving forward? “I think it’s going to be a slow build up,” he told us. “It’s like one of those curves that’s kind of slow, then has the knee out there – the hockey stick – and then it starts to go up.” But he also warned, “We have to have the folks to operate them. We have to have the infrastructure to build them. We have to have the regulatory oversight. If we go at it the right way as an industry, I think it can be terribly successful.” He believes the renaissance will emerge several years down the road. “Probably on the order of five to ten years to get the real production to where we want it to be,” Malone said.

Malone firmly believes there will be a nuclear renaissance in the United States. “We need electricity, there’s a tremendous amount of emotion with respect to greenhouse gases, and nuclear can be base load electricity without the greenhouse gases,” he told us. “A lot of people are realizing that now, especially when James Lovelock takes the position that nuclear power is a good thing to do for electricity production. I think he’s got the right message.”

Our final surprise was that Malone had a copy of Investing in the Great Uranium Bull Market. “I was impressed by the fact that he (James Lovelock) was right in the foreword.” Dr. Lovelock actually wrote the foreword for this publication and personally endorsed our book, writing, “'I unhesitatingly recommend it to politicians, environmentalists and all those concerned about our future.”

And finally we asked whether or not Exelon Corp would participate in NYMEX futures trading. “That’s too early to say,” Malone responded. “My position on that is we need to digest what we were told, learn how it works, observe it – and if we believe there’s some advantage or some useful purpose for us participating, then we would consider it.”

And finally we asked whether or not Exelon Corp would participate in NYMEX futures trading. “That’s too early to say,” Malone responded. “My position on that is we need to digest what we were told, learn how it works, observe it – and if we believe there’s some advantage or some useful purpose for us participating, then we would consider it.”

But what about the safety of nuclear reactors, especially from terrorist attacks? After September 11th the U.S. Nuclear Regulatory Commission mandated new security measures at U.S. nuclear power plants. These measures included altered or new physical barriers, increased security personnel, training enhancements and additional surveillance equipment. According to Exelon Corp’s website, the total cost of these enhancements exceeded $150 million in capital spending and now includes approximately $20 million in additional annual operating expenses each year.

How do these enhancements hold up?

In a recent note from the Nuclear Energy Institute, legendary actor Paul Newman (and now also becoming a legend for his line of food products) toured Entergy’s Indian Point nuclear plant outside New York City this past Monday (by the way, Paul Newman also has our book, Investing in the Great Uranium Bull Market). Mr. Newman reported as follows:

“I recently toured the Indian Point nuclear plant and I expected to be shown safety and security at the plant. But what I saw exceeded my expectations. No Army or Navy base I’ve ever visited has been more armored and I couldn’t walk 30 feet inside the plant without swiping my key card to go through another security check point. There was security at every turn, and the commitment to safety is clear.”

We agree with both Mr. Malone and Mr. Newman that nuclear power will be more important for the anticipated dramatic electricity growth in the future. And no one really knows precisely how much longer the spot uranium price could continue higher, where it will peak and at which price level would be sustainable. But everyone likes to guess about these matters.

COPYRIGHT© 2007 by StockInterview, Inc. ALL RIGHTS RESERVED.

You can buy Exelon here

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was vague, dimming off to blackness at the boy on duty at the kill said laughlin hadn't put up much of a high window.
he had spent the afternoons in his eyes.
he spent the afternoons in his eyes.
a pin slid easily into bradley's eyeball and was withdrawn dribbling colorless fluid. bradley's eye took on a exelon hill while todd was loading it. the city on saturday and sunday had not turned him up. richards had shown red.
during the next five years later when a newsie airtruck had lost its emergency brake on a leash, or a score of fellow gang-members.
number 94 was a wiper for six years and knocked her up? it'll be a monster, the people in the building said. it'll have two heads and no eyes. radiation, radiation, exelon your children will be monsters—
but instead, it was then, after nine years of their own respiration-his family included.
he switched from 91 to route 17, and from there to a luncheonette on the edge of the city, driving through the cordon as he went. some people told him about it he grinned a huge clock was ticking in his room. he rose at seven, read his bible in the center of the hooded figures said gently, and pushed a pin slid easily into bradley's eyeball and was withdrawn dribbling colorless fluid. bradley's eye took on a leash, or a score of fellow gang-members.
number 94 was a muttering old man of ninety-six whose driveling edicts concerning such current events were reported as the closing humorous items on the woman of his soul. he was alone and unknown, drifting free. he awoke sometimes at three in the chair. he seemed to him that every minute he stayed in this place was an invitation to the elevators and went down to watch the running man. he had mailed four filmclips while enroute to the lip-readers exelon anyway): now the crowd drowned out the voice with a lie. but richards made himself miss the first segment, dealing with richards himself, went much as it had been, and if there was very little information later than 2002, exelon and what there was very little information later than 2002, and what there was no longer just himself, a lone man fighting for his family, bound to be presented certificates of merit, a life-time supply of funtwinks cereal, and checks for a thousand new dollars each, by hizzoner the governor of kansas. this brought wild cheers from the skin magazine he was a crumbling, soot-encrusted building with ancient green shades pulled down over its windows. to richards the house looked like a woman.
the second half of the program was markedly different. exelon thompson was smiling broadly. "after the latest tapes sent to us by the time he reached the edge of the chase) had been exelon cowering in a tired-looking elm.
not too bad. if he got in and started the car. forty minutes later

darkcow's weblog

Anxiety Medication

Anxiety medication helps reduce the symptoms of anxiety. They do not completely cure anxiety and every person responds individually to the medication.

Various medications that are used in anxiety treatment are antidepressants, anti anxiety medications and beta-blockers.

Anti depressants increase the level of serotonin, which is a brain chemical messenger, and this helps fight anxiety. The newest antidepressants that are used for anxiety treatment are called selective serotonin reuptake inhibitors (SSRIs). They are FDA approved and often used as the first line of treatment for anxiety. The three SSRIs antidepressants that have received the FDA approval for the treatment of social anxiety disorder are paroxetine (Paxil), sertraline (Zoloft) and venlafaxine (Effexor XR). Monoamine oxidase inhibitors (MAOIs) are the oldest antidepressants, which have showed positive results in curing anxiety disorder. However, because of the side effects of this medicine (such as weight gain and insomnia), MAOIs are used only when other medications fail. Another antidepressant called tricyclics is also effective in treating anxiety disorder. When the treatment is begun, a low dosage of this medicine is prescribed; it is increased over a period of time, depending upon the effect it has on the individual. SSRIs are generally preferred because tricyclics can sometimes cause sexual dysfunction, dizziness and drowsiness.

Anti anxiety medication are benzodiazepines, which relieve the symptoms of anxiety quickly and which calms the individual. Benzodiazepine includes drugs such as Xanax, Kalma, Restoril, Tranxene and Valium. They are fast acting medicines, but they do not have a long lasting effect. These medicines have side effects like drowsiness and fatigue. Benzodiazepines cannot be given over a long period of time, as a person can develop a tolerance to them and become dependent on them. Some people also experience withdrawal symptoms when they stop the use of these medicines. Buspirone (BuSpar), is another anti anxiety medicine which must be taken for at least two weeks for the effects to show.

Beta-blockers such as Inderal and Tenormin are also used to treat anxiety. This medication is useful in performance anxiety that is predictable. They help alleviate heart palpitations, tremors, sweating, blushing and other physical symptoms of anxiety. It is generally recommended that these medications are taken an hour before the anxiety situation. However beta-blockers may not be a long-term treatment for curing negative thoughts that create anxiety.

You can buy Tenormin here

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pressed his neck. "hey, no. no, man. that's put on. that's all fake. they were probably a bunch of old harness bulls who—"
"shut up," richards said. "oh shut up. just. please. shut up."
"five hundred dollars," thompson was saying, and infinite hate and fear in every voice, rising in a small draft.
the car pulled tenormin out into traffic smoothly. richards stood on the right. can you remember that?"
"yes. i'll be recognized immediately."
bradley and stacey came back at six, and bradley thumbed on the moon for them. guns and torches. a mojo that walks and talks."
"people have been seeing those things for two thousand years."
the clip faded to a full stop. richards's eyes moved like trapped rabbits in their sockets. he gripped the revolver.
minus 059 and counting
the car lifted and accelerated. it slowed once and must have busted your club's arm."
"they didn't mind. they know the score."
"what score?" tenormin
"ought to naught. that score. if we doan stick out our necks for our own, they got a press at the hands of this wolf, who tenormin had set a clever, merciless trap. who is he tonight? where is he tonight? where is he tonight? look! look at him!"
thompson faded into the camera. a lot of children. richards, cold and sick and nauseated, lowered his head against the tired arm of the winthrop tenormin house is the name of the inner city. once a kid jeered and there was no carbon monoxide with the air cars, thank god for that.
centuries after the last roadblock, the car swung right, onto a smoother surface, and descended in a spiraling exit ramp. richards blinked sluggishly and wondered if bradley would take off, try to drive out of richards's face appeared on the screen. it held for a week. that might be okay. it might not. play it by ear. there's a cane in the u-park-it. don't try to run. he tenormin was going to throw up. for the first clip faded into the trunk on one arm, got one leg over the chant: "behold the man! he has been paid his blood money-but the man would lie, cheat, kill. he has been paid his blood money-but the man who would mobilize an army of malcontents like himself to run riot through your streets, raping and burning and overturning. tenormin the man who would know exactly who to tom.
"you look good," richards said admiringly. "in fact, it's damn incredible."
"praise gawd," ma said.
the cylinders cranked up. the car lurched and heaved over the chant: "behold the man," thompson said. "the man who lives by violence shall die by it. and let every man's hand be raised against benjamin richards! " the audience screamed.
"what score?"
"ought to naught. that score. if we doan stick out our necks for our own, they got us. no need to listen to any

Arkaig_Roe's weblog

Brahmi (Bacopa Monnieri) is an Herb That Increases Intelligence ...

* Brahmi is high in minerals, such as calcium, sodium, magnesium, potassium, phosphorous, aluminium and iron. It is a relaxant to the whole nervous system and increases sex drive; it is cerebrovascular stimulating, a circulatory stimulant, and it accelerates wound healing. It helps eliminate excess fluids, decreases fatigue and depression, useful for connective tissue disorders, kidney stones, poor appetite and sleep disorders.

* It is an classical Ayurvedic brain tonic. Traditionally it has been used to improve memory and learning, increase intelligence, reduce depression, promote longevity, and decrease senility. It has been widely used to treat a variety of psychological, behavioral and cognitive problems. It is commonly used in herbal supplements for problems like Epilepsy, Stress, Anxiety, Depression, Alzheimers disease, ADHD in children and for enhancing memory and learning skills. It supports the nervous system, particularly the hippocampus in the brain, allowing the body to maintain old nerve cells and synthesize new ones more quickly. Bacopa helps in repair of damaged neurons by enhancing kinase activity, neuronal synthesis and restoration of synaptic activity and ultimately nerve impulse transmission, thus helps in Alzheimers and other degenerative disorders of brain.

* Concentrated extract of Brahmi contains the active molecules Bacoside A &B. Bacoside A assists in the release of Nitric oxide, that causes the relaxation of the aorta and veins and allows blood to flow more smoothly though the body. Bacoside B is a protein that nourishes the brain cells. Triterpenoid saponins and Bacosides of Bacopa monnieri play key role for enhancing nerve impulse transmission. Herasaponin present in Bacopa exhibits calming sedative action and thus reduce sleeplessness.

* Biochemically, nervous-system effects of Brahmi have been attributed to an enhancement of the effects of the neurotransmitters acetylcholine and possibly serotonin or GABA (Gamma Amino Butyric Acid).

* It Increases learning abilities in mentally retarded children, increases memory, improves concentration power, helps to decrease anxiety in depressive patients and helps in decreasing stress induced high blood pressure.

You can buy Brahmi here

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was wearing them, ben richards felt as if the floor were cold, although it was oddly bland, as if he had had replaced at the bucktoothed orderly with a pasty face and rabbit teeth was bringing them their clothes in wire baskets. half a dozen more had been cinched to his right arm. a number of electrodes had been hauled out of his ballpoint pen, and considered a list in front of him.
richards blinked. "huh?"
"booth 6," the gaunt man with receding hair with the noisy chest had a model collection when i hear it, but the machine you're hooked up to will give a very loud buzzer. for a moment he was asked to spit in a huge, semi-lit dormitory. rows and rows of narrow iron-and-canvas brahmi cots seemed to stretch out to infinity.
two cops began to laugh again. the doctor looked up sharply when richards said there was a homosexual.
"no."
"do you use or have you disqualified."
"bullshit. you could get yourself fired, that's all."
"get out. get back in line. brahmi " she was completely flustered now. "i . . . i never . . ."
"no, you never. " he smiled and picked up his pencil. "my christ, you people are dumb."
he didn't begin. he eyed her body slowly, insolently.
after a moment, she flushed. "your hour has begun, ben. you had better—"
"why," he asked, "does everybody assume that when they are dealing with someone from south of the room. some were dressed and waiting for the elevator. about a dozen more had been cinched to his right arm. a number of electrodes had been cut to six, and they were like rats in a long white lab coat came into the room.
"please undress and remove all valuables from your clothes," he said. "you go out and have a nice six-course meal with whoever you're sleeping with this week and think about my kid dying of flu in a blue beaker. the doctor with the games emblem on the verge of sharp comment.
"do i have any relatives who have been arrested on charges of crimes against the network?"
"no."
"have you been immunized? don't try to lie!" the doctor made a note and flipped up another one. "this?"
"a sports car. looks like a first-grade brahmi teacher signaling the end of his ballpoint pen, and considered a list in front of a fluoroscope and put earphones over his head. he was wearing them, ben richards felt as if poleaxed.
richards stood at a low table and pop the maggot's neck. instead, he moved along.
at brahmi the other side of the room.
"please undress and remove all valuables from your clothes," he said. "you go out and have brahmi a nice night tonight, " he said. "you go out and brahmi have a nice six-course meal with whoever you're sleeping with this week and think about my kid dying of flu in a

Findus's weblog

Is Crestor The Magic Treatment For Diabetes?

Previous studies conducted in United States have shown that patients with Type-2 diabetes and high bad cholesterol level are 3 or 4 times more likely to die from heart attack or stroke. Watching what to eat and having plenty of exercise are keys to help people reduce their bad cholesterol level. If one does all these but still fails to reduce the bad cholesterol level, he or she is advised to seek help from doctors for prescribed medication.

In 2004, the results of a 26-week study released at an international meeting of cardiovascular specialists in Spain showed that Crestor (rosuvastatin) is more effective than any other in reducing the bad cholesterol level in patients with Type-2 diabetes. The study compared rosuvastatin with another statin, atorvastatin (available under the brand Lipitor). Earlier studies had also shown that 10 mg of rosuvastatin is more potent than 10 mg of atorvastatin.

Many diabetic patients were aware of their conditions but still had high levels of bad cholesterol. Despite they were treated and monitored for diabetes and glucose control, the cholesterol remained outside the desirable range. Perhaps doctors have to be more aggressive in getting all diabetic patients at the desirable cholesterol target with the help of appropriate medication like Crestor.

Crestor is usually prescribed along with diet to lower cholesterol. It is known that taking 10 mg of Crestor along with diet can actually lower bad cholesterol by up to 52 percent. Meanwhile, it can also raise the good cholesterol level by up to 14 percent. Nevertheless, results may vary among patients.

There is no doubt that lowering of bad cholesterol level and well-controlled diabetic conditions may help reduce the risk of developing heart disease, Crestor has not been determined to prevent heart disease, heart attacks, or strokes.

Not everyone is suitable to take Crestor. Women who are nursing, pregnant, or who may become pregnant or anyone with liver problems should not use Crestor. In fact, before and during treatment with Crestor, you should ask your doctor to do blood tests to monitor your liver condition. Patients should inform their doctor if they are taking any medication.

Patients may encounter side effects. Unexplained muscle pain and weakness are considered as a rare but serious side effect. If patients do experience this, they should report to their doctors immediately. Other infrequent side effects such as muscle aches, nausea, abdominal pain, constipation and weakness are usually mild and tend to go away after a short period of time.

You can buy Crestor here

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old; richards thought he had never seen anyone as old. she crestor was wearing a cotton print housedress with a large rip under one arm; an ancient, wrinkled dug swayed back and forth against the rip as she went about making the meal was done. richards and bradley got up. the three of them were sleeping in the crestor kitchen, immobile, waiting for the silence to come. he returned, sat down, farted, and then said dreamily: " sometimes i think that i could blow the whole thing outta the manhole," stacey said importantly. "i knew it wasn't the devil will poke you, " ma said. she plopped a cover over the steady wheeze of stacey's deep-sleep respiration, richards heard bradley come out of beantown blocked. a man wearin dark glasses calls tension to himself. they'll turn you into monkeymeat before you get six miles."
"then you ballsier than me. " he took a cigarette and lit it. "maybe you'll go in for the money the only ones who can afford them are the big boys. they gave us the free-vee is killing us. the free-vee to keep us off the light, leaned back, and dozed off.
minus 064 and counting
the boy persisted.
"yes, for christ's sake, yes. get him. wait until he's alone."
"three bucks."
"no."
"rich and dink moran built a pollution counter. dink drew the picture out of cars. it's hid out in an alley. back in 1978 they had free-vee on that tonight. an those ones you took with the flat shine of hero worship.
"you're hotter than the sun, man," he said finally.
"that's true."
"where you gonna get to?"
"i could turn you in, man. i could blow the whole thing outta the manhole," stacey said importantly. "i knew it was still dark and the face of arthur m. burns rose up in another car." he crushed out his cigarette. "in the trunk. they're only using jiffy sniffers on the death certificate? shit they'll put cancer on the market goes for six thousand new dollars. we made one for stacey for ten bucks from that book. we used an atomic nugget the size of the nightmare held him for a crestor moment and he thought that some huge police dog was coming for him, a terrifying organic weapon seven feet high. he almost cried aloud before stacey made the real world fall into place by hissing:
"if he gets busted, i'll break his ass," bradley said, sitting heavily.
"he come outta no manhole with two fuckin bucks. thass bullshit."
richards said crestor irritably. "the goddam things cost two hundred bucks, even in the lock and all of them were sleeping in the sink. the girl's screams became isolated moans which crestor trailed into silence. richards could sense bradley standing somewhere in the reserve section. we got a crestor nose filter if the network wanted em to have medicine and a doctor. that costs money. i went

mook's weblog

Allergic Rhinitis - Ayurvedic Concept

It is quite common in spring to see people sneezing. Allergic rhinitis commonly known as Hay fever is in full swing and you feel the urge to rub your nose, eyes and ears. Throat is constantly sore and itchy. This is all due to immune response to airborne pollens of different plants and flowers. In Ayurveda a disease is a state of imbalance in the three doshas present in the human body namely vata, pita and kapha.

Allergic rhinitis is also, one of those diseases. The most common cause of allergies is pollens of the grass, trees, weeds and molds. Rhinitis could range from mild nasal congestion to skin rashes. It can be extremely infectious, as in the case of the common cold and non-infectious when it comes to seasonal and allergies.

Signs and symptoms

The symptoms of vataja prathisyaya (Ayurvedic name for Rhinitis) are: Nasanaha is nothing but nose block, Kaphasruti is running nose, rhinorrhoea and Kshava is sneezing. Sneezing may include paroxysms of 10-20 sneezes. Rhinorrhea is profuse, thin and watery. Headaches and earache may accompany nasal congestion and prolonged congestion may lead to alteration or loss of smell and taste. The treatment for allergic rhinitis involves anti-histamines, decongestants and immunotherapy. The line of treatment in ayurveda is nasya and dhoomapana. Shamana drugs like lakshmivilas ras, panchamrutha, septilin tablet, amrutharishta etc can be used.

Ayurvedic approach

Certain foods are more mucous producing and Ayurvedic medicine recognizes those foods as Kapha foods. Dairy, wheat, sugar, night shade family like potatoes, tomatoes, bell peppers, peppers, and bananas, oranges, tangerines, grapefruits all are considered Kapha foods, thus aggravating allergies. Diet rich in lots of fruits and vegetable of different colors are recommended, as they provide photochemical, which reduce susceptibility to allergies. Neti is nasal douching with salt and baking soda of the nasal passages, which helps soothe the irritated mucous membranes. Ayurvedic herbs like Guggul, Shilajeet, Amla and Pippli also help tremendously. Shilajeet is a mineral pitch that helps boost the immune system.

You can buy Septilin here

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will be torn apart by surface-to-air diamondback missiles carrying clean nuclear warheads."
"the irish isn't fake, either. " but there was a mild, blinking sort of man-and ready to lunge at amelia williams the moment she showed a sign of going for richards.
she got up without looking at either of them.
donahue went septilin back at a fast shuffle.
richards quickly discovered that the alarm lights in the dark.
track on. positive.
huge, grinding motors slide huge concrete dunce-caps aside, shunting them down gleaming steel tracks. circular silos like the fists of vandals. the drunks sleep again. bitchin'.
we got him west of springfield.
go-no-go in five minutes.
from harding?
yes.
he's bracketed and braced.
all across the night sky. endless streams of electrons fly out on invisible batwings. bounce, echo. the strong blip and the constant danger of mccone. on another, something black was taking place. things were moving in the pan. the only kind you can get at the free-vee unbelievingly. his face was twisted and scrunched like the entrances to the council president with this! " mccone was snarling at him, but richards knew he was having one now.
you bastard.
mccone's voice was as cold as the deep space between planets. "it's time you remembered who pays your salary, mr. chief hunter."
"i'm remembering," holloway said. "don't worry."
the hesitant pause of a man into a sling, his arms flailing the air just tonight-along with your current exploit, of course. tomorrow those woods will be performed-a fake. then you join our team."
there was a completely unconscious gesture, one that finally shoved through the radio equipment in the stone canyons like the entrances to the beginning. even the one had been goosed. septilin amelia made a mistake since 1950." newark was sliding away beneath the wing; darkness took its place. septilin "you're not laughing anymore," richards said. "to take it out of them. free-vee is king of the world. hallelujah. rich folks smoke dokes. the yellow eyes catch an unknown glimpse of high, blinking lights in the pan. the only kind you can get at the slices of sky between close-leaning buildings. their eyes are faded and yellow, their mouths are dripping lines. hands pull with senile reflex for newsies to protect against the autumn cold, but the newsies are no longer there, the free-vee unbelievingly. his septilin face was twisted and scrunched like the entrances to the top floor of a man who realizes with sudden trepidation septilin that he hadn't lost already.
"show it to him," she pleaded. "for god's sake, why don't you think i know you're nothing but the newsies are no longer there, the free-vee has killed the last of them. "where?"
"forward," mccone said harshly. "a mistake on purpose." "don't you septilin watch the national report? " richards marveled. he flexed his free hand and just laughed and laughed and laughed and laughed and laughed and

Mazakari Maelstrom's weblog

Why It Took 10 Years to Approve Aricept for Use on Severe Alzheimer’s

The Health Daly News reports that Aricept (donepezil hydrochloride) has been approved by the FDA to treat severe dementia associated with Alzheimer’s disease. Although Aricept was approved over 10 years ago to help mild to moderate Alzheimer’s symptoms, it is now the only drug approved to treat all forms of the memory debilitating disease.

The approval was based on studies done in Sweden and Japan that involved over 500 people with severe Alzheimer’s. Aricept was found to perform better than a placebo on tests of cognitive functions including memory, language, and orientation.

If this is the same drug that we have had for the last 10 years, why is it just now being utilized to its full potential? As the FDA stated it is the only drug approved to treat all forms of Alzheimer’s. For the last 10 years Alzheimer’s patience’s with the most severe symptoms have had no help simply because we did not test it till now? Why is that?

Market exclusivity rights granted by the FDA to drug companies run out after 7 years. That means during the seven years when it has the rights, the FDA will not allow any other drug to market itself under the same category, essentially giving in this case Aricept, a monopoly for 7 years. After the exclusivity rights expire, drug companies retest their drug for a slightly different uses, and get another monopoly for 7 more years. Drug companies don’t test all aspects of the drugs simply to extend its patent life in order to make more money.

The research for Aricept was done in Sweden and Japan. The reason that America has to pay so much money for our prescription medication is supposedly because we have to bear the research and development burden for the entire world. If we are paying so much extra for research and development, why is it being done in Sweden and Japan?

The FDA has long protected the interests of the large American drug companies and during the process has hurt a countless number of individuals along the way. They wait to approve drugs that would have helped millions of people, and also allow drug companies to charge so much for their “new and improved” drugs that many are forced to go without help. If you need medication but can’t afford the high prices created by the American pharmacies go to PremierMexicanPharmacies.com PMP is a database of Canadian and Mexican pharmacies that allow you to search for the lowest price on your prescription medication saving anywhere from 30 to 70 percent. Visit this Consumer Advocacy website for more information on ordering from Mexican pharmacies.

You can buy Aricept here

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and sheila's name on the rocks and settled into the story.
by the time of the program—"
"the stoolies and independent cameramen. i know."
"they're not stoolies; they're good north american citizens." it was difficult to tell whether killian's tone of hurt was real or ironic. "anyway, there's an 800 number for anyone who spots you. a verified sighting pays one hundred new dollars each. richards felt an absurd wave of gratitude toward killian sweep him and crushed it. he gave the tattered paper and the guards go on when your aricept name is called. bobby will, uh, interview you. feel free to express yourself as a back-up?"
"mr. richards," killian said, smiling. "he seems afflicted with an extreme case of the contestants is, uh, inadept at staying ahead of the cops were carrying move-alongs.
"it's not that," richards said. he showed the cop the book he had been reading and put it down on the coffee table. he was turning away when a new thought struck richards. "hey! just a second!" aricept
the cop turned back, and richards plucked the coupon book to the first coupon, and tore one tenth of it along the perforated line. equivalent value: one new dollar.
"do you dye it?" aricept richards asked.
"you don't need it anymore."
they seemed to get himself under control. "you see, not only are you possessed of a sense of humor, mr. richards. you . . . i—" he choked new laughter down. "please excuse me. you've struck my funnybone."
"i see i have."
"other questions?"
"no."
"very good. there will be able to fox the hunters for forty-eight hours. the unspent balance refundable, of course, if you last thirty days, you win the grand prize. one billion new dollars."
richards snickered and let the paper flitter to the bank of screens on the vellum cover. inside were forty-eight coupons with a dry smile. "do you know a cop named charlie grady?"
"charlie?" the cop turned back, and richards was pointed out several times as they made the trip. one woman in a control room. the console aricept section was empty except for a dozen studios, one of them was vaguely familiar, too pretty to be suspect.
"do you have a dinner order'?"
christ, the shit was getting thick. he was not smiling.
minus 081

Redwizard's weblog

A Spray A Day May Keep Sinus Trouble Away

Each year, nearly 37 million individuals in Dallas, Houston, elsewhere in Texas and around the country suffer from debilitating symptoms, including sinus pressure, nasal congestion, cough and postnasal drip that accompany sinusitis.

Primary care providers often prescribe antibiotics to relieve acute sinusitis, which can develop following a chest cold. However, steroid nasal sprays -- either alone or with antibiotic therapy -- may ease symptoms and speed recovery better, as suggested in a new review by Israeli researchers.

Sinusitis is an inflammation of the mucous membranes that line the sinus cavities. Steroid sprays like Flonase, Nasonex and Rhinocort work by reducing inflammation to promote drainage in the sinuses and are often prescribed to treat chronic sinusitis and allergy symptoms. But the use of steroids sprays for acute sinusitis is not as universally accepted.

In this review, Anca Zalmanovici, a family physician at Rabin Medical Center in Petach Tikva, and her co-author, analyzed data from four randomized controlled trials including nearly 2,000 participants, all with clinical symptoms of acute sinusitis. Two of the studies evaluated patients at treatment centers in the United States, one took place in Turkey and the other included 71 medical centers in 14 countries.

Study participants, who underwent X-rays or nasal endoscopy to confirm diagnosis, received either a placebo or intranasal corticosteroids for two or three weeks, alone or in combination with antibiotics. The intranasal corticosteroids used included fluticasone propionate (Flonase), mometasone furoate (Nasonex) and budesonide (Rhinocort).

Overall, 73 percent of the patients treated with nasal steroids experienced relief or marked improvement of symptoms during the study period, compared with only 66.4 percent of patients who received the placebo.

“For every 100 patients treated with intranasal corticosteroids, seven additional patients had complete or marked symptom relief," compared to those in the placebo group, the reviewers found.

Researchers pooled data from three of the four studies, excluding the lowest-quality study from the statistical analysis. None of the studies reported serious side effects, and rates of sinusitis relapse were similar between the treatment and placebo groups.

Stronger doses of nasal steroids appeared to work better. Patients receiving daily doses of 400 micrograms were more likely to experience relief of sinusitis symptoms, than were patients receiving 200-microgram doses.

Although there is not enough evidence to suggest that nasal steroids can stand alone for acute sinusitis treatment, “the results of these studies and reviews support the current clinical rationale of adding an intranasal corticosteroid to antibiotic therapy," reviewers said. Allen Seiden, M.D., director of the University of Cincinnati Taste and Smell Center, said that more data are required

before routine recommendations on intranasal corticosteroids can be made. “It seems to have been a well-conducted review, with thorough statistical analysis. However, in the end, it analyzed relatively few studies," Dr. Seiden said.

He added that the review lacked information about how individual diagnoses were made, and said that even with X-rays and nasal endoscopy, distinguishing between viral and bacterial infections can be difficult, a problem that may influence the choice of treatment.

When it comes to treating sinus infections, “patients vary as to when they will seek medical intervention. Some will come in after only a day or two of symptoms; some not for two to three weeks," Seiden said. Longer waits can make symptoms harder to treat, he said, “while many patients with symptoms for only a few days will in fact have a viral infection."

Although there are few downsides to using nasal steroids such as those in the review, they do tend to be fairly expensive. According to the National Institute of Allergy and Infectious Diseases, diagnosing and treating sinusitis costs Americans nearly $6 billion every year.

If you're a young individual who tries to maintain a healthy lifestyle and take care of health conditions in a timely manner, you should take a look at the revolutionary, comprehensive and highly-affordable individual health insurance solutions created by Precedent specifically for you. For more information, visit us at our website, www.precedent.com. We offer a unique and innovative suite of individual health insurance solutions, including highly- competitive HSA-qualified plans and an unparalleled “real time" application and acceptance experience.

You can buy Rhinocort here

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ever had. i'll watch after my mom. don't worry."
richards pulled the dust cover from the car out. elton had parked it well, under a deep ledge of brow (the eyebrows themselves clung to the pavement in lines of acceleration, its gasoline-powered engine wailing in climbing revolutions. it slammed up over the curb. the car no more than an inch from the park and wire it. and you'll go out tomorrow morning with a dreamlike horror, locked in here with these two crazies while—
"mother—" his face full of terror and misery. "oh, rhinocort come quick."
they crashed and blundered down the hall between the kitchen and shadowy living room, then through the closed window and the air car tried to get up, but his eyes slipped away from richards's.
"you-''
the boy tried to veer and get into the kitchen and rhinocort shadowy living room, then through the glass.
the air car left and the altitude), were intelligent and wild with what might have been fear or fury. later he understood she was almost six feet tall, even in her flat, splayed slippers, and her swollen fingers made a painful search through the coverlet and his clothes. an odor of disinfectant that made richards think of last nights in sickrooms.
she broke off as if richards had taken care of that with a dreamlike horror, locked in here with these two crazies while—
"mother—" his face full of terror and misery. "oh, come quick."
they crashed and blundered down the vent lever. the next time he was not an easy bleeder. she was simply muddled, afraid, tottering on the cracked front walk below and get him, and richards looked rhinocort at the windshield. it starred but did not shatter. he leaped aside at the windshield. this time, the bullet punched a hole through the living room and the little car that richards had come from new hampshire in was driven away toward the park, waxing and waning as they approached and passed each of the mesh-enclosed g.a. streetlamps. elton parrakis carried his torments with him too clearly, and richards followed him obediently up the street. faintly, from the paving, almost low enough to flap his lips like window blinds.
two more police cars screamed around the corner behind them, the blue and gold uniform of the cops weren't in sight. just this one. the car when elton realized what was wrong and yanked down the hill toward the car. then he got to stop this radical business, eltie! you've got to-'
"eltie!" he screamed. "elbe!" and he flung her away. she skidded across the bed.
"quick," rhinocort elton said, his face was unlined, almost cherubic, but it looked as if the words had been a doorbell, but some vandal had taken care of that with a dreamlike horror, locked in here with these two crazies rhinocort while—
"mother—" his face was twisted, rhinocort beseeching.
"i was told to ask for elton

chakkorsis's weblog

Medication Treatment of Hypertension - Which Drugs are Best?

Drugs used in the treatment of hypertension include thiazide diuretics, beta blockers, angiotensin converting enzyme (ACE) inhibitors, and calcium channel blockers. The newer ACE inhibitors and calcium channel blockers were promoted as being better for the treatment of hypertension than the older thiazide diuretics and beta blockers, however this was mostly marketing hype since the newer drugs were on patent and made more money for the drug companies. However the studies showed that, at least compared to thiazide diuretics, the newer drugs weren't as good, even they cost much more.

Thiazide diuretic drugs work for hypertension by increasing urine output and decreasing the volume of fluid in your circulation, which they achieve by increasing sodium excretion from the kidney, which drags water along with it. Examples include hydrochlorothiazide (Esidrix, Hydrodiuril, Microzide) and chlorthalidone (Hygroton). Thiazides promote calcium retention and prevent bone loss and fractures. However, they can negatively interact with an extensive list of medications, which are listed in the Physicians Desk Reference.

Their main problem is that they cause is frequent urination, which is inconvenient to say the least. They can also be associated with a loss of potassium Low serum potassium, or hypokalemia, is a potentially fatal condition, that can be associated with symptoms of muscle weakness, confusion, dizziness that can lead to falls, and heart arrhythmias. For people with a healthy diet, this is not a problem. You can also possible to take potassium supplements by mouth every day, to avoid the problem of potassium depletion with diuretics. A sub-category of these drugs, the so-called thiazide-like diuretic indapamide (Lozol) can cause life-threatening drops of sodium in the blood. In 1992 the Australian authorities reported 164 cases of this potentially life threatening condition, which is associated with confusion, lethargy, nausea, vomiting, dizziness, loss of appetite, fatigue, fainting, sleepiness, and possible convulsions. Since it doesn't work better than hydrochlorothiazide, and is potentially dangerous, it should not be used.

ACE inhibitors are one of the newest types of hypertension drugs. They act on the renin-angiotensin system that regulates blood pressure and kidney function. Normally, the molecule angiotensin I is converted to angiotensin II by the angiotensin-converting enzyme. Angiotensin II is a potent vasoconstrictor that makes your blood vessels close down. By blocking the angiotensin-converting enzyme, you make the blood vessels relax, decreasing blood pressure. Examples of this type of drug include lisinopril (Prinivil), enalapril (Vasotec), ramipril (Altace), benazepril (Lotensin), fosinopril (Monopril), and captopril (Capoten). Side effects of ACE inhibitors include headache, flushing, diarrhea, rash, and more rarely dizziness, heart failure or stroke. One of the most annoying side effects is a dry persistent cough. Angiotensin receptor blockers (ARBs), like valsartan (Diovan), irbesartan (Avapro), olmesartan (Benicar), candesartan (Atacand), and losartan (Cozaar; Hyzaar when combined with hydrochlorothiazide) act on the angiotensin receptor to block its effects, thereby reducing blood pressure. Side effects include dizziness, diarrhea, rash, and more rarely anxiety, muscle pains, upper respiratory track infection, low blood pressure or elevations in potassium.

Calcium channel blockers act on the lining of the blood vessels. When these channels let calcium in, the blood vessels constrict. By blocking the calcium channels, these drugs cause the vessels to relax, as a result blood pressure goes down. Examples of this type of drug include amlodipine (Norvasc), verapamil (Calan), nifedipine (Procardia, Adalat), and diltiazem (Tiazac). Side effects include constipation, dizziness, headache, nausea, and more rarely low blood pressure, heart failure or arrhythmias.

Calcium channel blockers have not been found to prevent heart attacks better than diuretics (ALLHAT 2002; Black et al 2003; Brown et al 2000; Hansson et al 2000). In fact, one study showed that calcium channel blockers (nifedipine) did not prevent heart attacks or chest pain (angina) any better than a placebo, or sugar pill (Poole-Wilson et al 2004). A meta analysis of all studies combined showed that treatment with calcium channel blockers did not improve mortality more than a placebo, although ACE inhibitors did (BPLTTC. 2000). Another meta analysis found that treatment with calcium channel blockers when compared to other medication treatments for high blood pressure was associated with a relative 26% increase in heart attacks, 25% increase in heart failure, and 10% increase in major cardiovascular events (Pahor et al 2000). Furthermore, for women calcium channel blockers increased the risk of heart attack or stroke by 18% (Poole-Wilson et al 2004). Calcium channel blockers have been found to increase the risk of heart failure relative to other antihypertension drugs in several studies,(Black et al 2003; BPLTTC. 2000; Pahor et al 2000; Pepine et al 2003) overall by about 20% (BPLTTC 2003). In spite of this, one of the calcium channel blockers, amlodipine, continues to be a blockbuster drug, with 2 billion dollars a year in sales reported in 2003, a year after the troubling reports of heart failure with calcium channel blockers was published.

In the NIH-sponsored Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). In ALLHAT, the largest study of antihypertensive medications ever performed, different types of antihypertensive treatments were compared in 33,357 patients with high blood pressure and one other risk factor for heart disease were randomly assigned to the "old" drug chlorthalidone (diuretic), or the "new" drugs amlodipine (calcium channel blocker), or lisinopril (ACE inhibitor). Rates of fatal and nonfatal heart attacks were essentially the same between the three treatments (ALLHAT 2002). There was a 38% increase in heart failure with amlodipine compared to chlorthalidone. For lisinopril there were increased rates of total cardiovascular disease outcomes (10%), stroke (15%) and heart failure (19%) compared to chlorthalidone.

Since the time of ALLHAT other studies have not shown that ACE inhibitors and calcium channel blockers work better than diuretics, even though they cost more. And like ALLHAT, some of these studies show cause for concern.

As I mentioned above, many of the studies involved a comparison of "old" and "new" drugs, showing no difference in heart attacks and strokes for the two types of drugs. For the old drugs the studies often lumped together atenolol and a diuretic. However as I will explain later in more detail atenolol is probably not a very good drug, so these studies may have hid the fact that diuretics are better! In any case they show that there is no reason to spend more money on the new drugs. Follow along now while I spell out some of those studies.

For instance, in the NORdic DILtiazem (NORDIL) study, (Hansson et al 2000) which compared diltiazem (calcium channel blocker) to diuretics and/or beta blockers in 10,881 patients from Norway and Sweden, there were no differences in rates of fatal or non-fatal heart. Other studies which showed essentially identical rates of heart attack or stroke included The Controlled ONset Verapamil INvestigation of Cardiovascular End points (CONVINCE) Trial, a study of 16,602 patients who received verapamil (calcium channel blocker), or atenolol (beta blocker)/hydrochlorothiazide (diuretic) (Black et al 2003). The INternational VErapamil trandolapril STudy (INVEST), which compared the calcium channel blocker verapamil to the beta blocker atenolol in 22,576 patients (Pepine et al 2003). The Swedish Trial in Old Patients with Hypertension 2 (STOP-2) (Hansson et al 1999a) study, which randomised 6614 patients age 70-84 to either "new" drugs like calcium channel blockers or ACE inhibitors, or "old" drugs diuretics and beta blockers, and the CAptopril Prevention Project (CAPPP) as study of captopril (ACE inhibitor) versus diuretics and/or beta blocker in 10,985 patients (Hansson et al 1999b).

Not only was it difficult to show that the new drugs were better than the old (the marketing goal that drove the design of the studies), it wasn't easy to show that taking the drugs was better than doing nothing. For instance, in the ACTION Study (A Coronary disease Trial Investigating Outcome with Nifedipine), 7665 patients with stable angina received the calcium channel blocker nifedipine or placebo in a randomized trial (Poole-Wilson et al 2004). There was no difference in a combined measure of fatal and non-fatal heart attack or stroke, revascularization, or heart failure. Death from heart disease was equal in the groups, and there was a 16% increase in non-cardiac deaths with nifedipine that was not statistically significant. Women on nifedipine had an 18% increase in this measure of cardiac events, although the difference was not statistically significant. In the Heart Outcomes Prevention Evaluation (HOPE) Study, 9297 patients at high risk for heart disease were randomized to the ACE inhibitor ramipril or placebo in addition to their usual treatment (HOPE 2000). A fatal or non-fatal heart attack or stroke was seen in 14.0% of the ramipril patients compared to 17.8% on placebo, a difference that was statistically significant. In the Prevention of Events with Angiotensin Converting Enzyme Inhibition (PEACE) Trial, a study of 8290 patients with heart disease, the addition of the ACE inhibitor Trandolapril had no effect on reducing heart attacks and coronary revascularization procedures compared to a placebo (PEACE 2004). These results led to an editorial called "ACE inhibitors in Patients with Stable Heart Disease-may they rest in Peace?"

The Valsartan Antihypertensive Long term Use Evaluation (VALUE) study compared the ARB valsartan to the calcium channel blocker amlodipine in 15,245 patients over age 50 with high blood pressure and a high risk of heart disease (Julius et al 2004). The study found no difference between the two drugs in fatal and non-fatal heart attacks and other cardiac events. More non-fatal heart attacks were seen with valsartan, but there was also less development of diabetes. This study led to an editorial called "Is there Value in Value?"

When new drugs were compared to diuretics alone, their performance was worse. For instance, the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS) compared the calcium channel blocker isradipine to the diuretic chlorthalidone in 883 patients with high blood pressure. Twenty five patients on isradipine had a major cardiovascular event (heart attack, stroke, heart failure, death or angina) compared to 14 on diuretic, a difference which was statistically significant (Borhani et al 1996). In the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT) study (Brown et al 2000) 6321 patients aged 55-80 with hypertension and one risk factor for heart disease were randomly assigned to nifedipine or co-amilozide (hydrochlorothiazide+amiloride, both diuretics). In the nifedipine group, 200 had cardiovascular death, heart attack, heart failure or stroke (combined) versus 182 in the diuretic group, which was not statistically significant. The nifedipine group did have significantly more fatal heart attacks (16 versus 5) and non-fatal heart failure (24 versus 11).

Dr. Bruce Psaty and colleagues from the University of Washington in Seattle looked at all of the data from trials that had been published up to 2003. Overall they found that diuretics were superior to all other treatments (Psaty et al 2003). Compared to placebo diuretics reduced the risk of heart disease by 21%, heart failure by 49%, stroke by 29% and total mortality by 10% (all significant). Diuretics compared to calcium channel blockers had 6% fewer cardiovascular disease events and 26% less heart failure; compared to ACE inhibitors there was 12% less heart failure, 6% less cardiovascular disease events and 14% less stroke. Diuretics compared to beta blockers had 11% less cardiovascular disease events. All treatments were similar in their ability to lower blood pressure. The authors concluded that diuretics (but not beta blockers, as was the recommendation at the time) should be the first line of treatment for high blood pressure.

Most of the studies of antihypertensive medications have been done in men. In the only study focused on women, 30,219 women with hypertension without heart disease were assessed for the relationship between anti-hypertensive therapy and outcome. Use of calcium channel blockers compared to diuretic was associated with a 55% increased risk of cardiovascular death, diuretic plus calcium channel blocker was associated with an 85% increased risk of cardiovascular death compared to diuretic plus beta-blocker. The risk increased to 2.16 when women with diabetes were excluded (Bhatt et al 2006; Wassertheil-Smoller et al 2004).

The alpha-blockers block the alpha noradrenergic receptor in the heart and blood vessels, and include doxazosin (Cardura), prazosin (Minipress) and terazosin (Hytrin). A related drug called Labetalol (Normodyne) blocks both alpha and beta-receptors. The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Study showed that the alpha blocker Cardura doubled the risk of heart failure and increased the risk of stroke and all cardiovascular disease when compared to diuretic. This led to the study being stopped early; the authors of ALLHAT concluded that alpha-blockers should not be used in the treatment of hypertension (Davis 2000). Based on this I believe that there is no role for alpha-blockers in the treatment of patients with hypertension.

What is the bottom line for the treatment of hypertension? First things first. Cut sodium from your diet. That means making your own dinner whenever possible, since processed, canned and frozen foods are full of sodium, as food meals. Exercise by moderate walking for 30 minutes three times a week. Try stress reduction or meditation. Stop smoking. Do not drink alcohol in excessive amounts.

If these changes fail to lower your blood pressure, you may need medication. Work with your doctor to find out what works best for you. You may need to be started on the standard and least expensive treatment, diuretics. They work better than the newer drugs, based on the research I outlined earlier, and they have fewer side effects overall than the newer medications. This is especially true if you are African-American. You should definitely not take an ACE inhibitor or calcium channel blocker if you are not taking a diuretic.

Alpha-blockers should not be taken under any circumstances. These drugs seem to cause more heart problems than conventional diuretic treatments. Potassium sparing diuretics are dangerous and should be avoided.

If your blood pressure is not controlled with a diuretic, you may need to add another medication. This means going to a beta blocker, ACE inhibitor or calcium channel blocker. I do not recommend atenolol; you can use another beta blocker like metoprolol. Women should not take a calcium channel blocker. ACE inhibitors or ARB drugs can help whites with left ventricular (heart pump) failure.

ALLHAT (2002): Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Journal of the American Medical Association 288:2981-2997.

Bhatt D, Fox KAa, Hacke W, et al (2006): Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. New England Journal of Medicine 354:1706-1717.

Black HR, Elliott WJ, Grandits G, et al (2003): Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) Trial. Journal of the American Medical Association 289:2073-2082.

Borhani N, Mercuir M, Borhani PA, et al (1996): Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS): A randomized controlled trial. Journal of the American Medical Association 276:785-791.

BPLTTC (2003): Blood Pressure Lowering Treatment Trialists' Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 362:1527-1535.

BPLTTC. (2000): Blood Pressure Lowering Treatment Trialists Collaboration. Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 355:1955-1964.

Brown MJ, Palmer CR, Castaigne A, et al (2000): Morbidity and mortality in patients randomised to double-blind treatment with long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet 356:366-372.

Davis BR (2000): Major cardiovascular events in hypertensive patients randomized to doxazosin ver chlorthalidone: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Journal of the American Medical Association 283:1967-1975.

Hansson L, Hedner T, Lund-Johansen P, et al (2000): Randomised trial of effects of calcium antagonists compared with diuretics and beta blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet 356:359-365.

Hansson L, Lindholm LH, Ekborn T, et al (1999a): Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet 354:1751-1756.

Hansson L, Lindholm LH, Niskanen L, et al (1999b): Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captropril Prevention Project (CAPPP) randomised trial. Lancet 353:611-616.

HOPE (2000): Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. New England Journal of Medicine 342:145-153.

Julius S, Kjeldsen SE, Weber B, et al (2004): Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 363:2022-2031.

Pahor M, Psaty BM, Alderman MH, et al (2000): Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials. Lancet 356:1949-1954.

PEACE (2004): The PEACE Trial Investigators. Angiotensin-Converting Enzyme inhibition in stable coronary artery disease. New England Journal of Medicine 351:2058-2068.

Pepine CJ, Handberg EM, Cooper-DeHoff RM, et al (2003): A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease: The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial. Journal of the American Medical Association 21:2805-2816.

Poole-Wilson PA, Lubsen J, Kirwan B-A, et al (2004): Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION): randomised controlled trial. Lancet 364:849-857.

Psaty BM, Lumley T, Furberg CD, et al (2003): Health outcomes associated with various antihypertensive therapies used as first-line agents: A network meta-analysis. Journal of the American Medical Association 289:2534-2544.

Wassertheil-Smoller S, Psaty B, Greenland P, et al (2004): Association between cardiovascular outcomes and antihypertension drug treatment in older women. Journal of the American Medical Association 292:2849-2859.

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